Glucan and Cathepsin D patents and papers

	My Patents Glucan (US) (2 patents) Yvin, J.C., Vetvicka, V.: Therapeutical treatment, US Patent # 6,660,722 Full version of the patent can be found here Yvin; J.C, Panak; E., Vetvicka; V.: Therapeutical combination against cancer US Patent # 7,070,778 Full version of the patent can be found here Glucan (EU) (4 patents) USE OF LAMINARIN IN THE TREATMENT OF CANCER Inventor: YVIN JEAN-CLAUDE [FR] ; VETVICKA VACLAV [US] Applicant: GOEMAR LAB SA [FR] Publication info: EP1448215 (A2) — 2004-08-25 IPC: A61K36/02 ; A61P31/04 ; A61P31/10 (+27) 2 OLIGO–BETA–(1,3)–GLUCAN AND MONOCLONAL ANTIBODIES AGAINST CANCER Inventor: YVIN JEAN-CLAUDE [FR] ; PANAK EDOUARD [FR] (+1) Applicant: GOEMAR LAB SA [FR] Publication info: EP1684770 (A1) — 2006-08-02 IPC: A61K31/702 ; A61K31/715 ; A61K39/395 (+7) 3 CHEMOTHERAPEUTIC ANTINEOPLASTIC TREATMENT Inventor: YVIN JEAN-CLAUDE [FR] ; VETVICKA VACLAV [US] Applicant: LAB GOEMAR SA [FR] Publication info: EP1663260 (A1) — 2006-06-07 IPC: A61K31/675 ; A61K31/716 ; A61P35/00 (+6) 4 PHARMACEUTICAL COMPOSITIONS AND THERAPEUTIC TREATMENT WITH OLIGO–BETA– (1,3) – GLUCANS Inventor: YVIN JEAN-CLAUDE [FR] ; JAMOIS FRANK [FR] (+1) Applicant: LAB GOEMAR SA [FR] Publication info: EP1663258 (A2) — 2006-06-07 IPC: A61K31/702 ; A61K31/716 ; A61K45/06 ALL EU PATENTS Cathepsin D: Our research group has recently been awarded a US Patent #5,800,814 covering the clinical applications of the procathepsin D inhibitors in cancer treatment Full version of the patent can be found here (US Patent and Trademark Office) SELECTED BIBLIOGRAPHY (out of 150) Free articles from ScienceDirect (click here) GLUCAN: Vetvicka V., Vetvickova J., Jamois Frank, J-C Yvin: Enhancing effects of new biological response modifier B-1,3 Glucan sulfate PS3 on immune reactions. Biomedicine & Pharmacotherapy 62, 2008 PDF DOCUMENT Vetvicka V., Vetvickova J.: A Comparison of Injected and Orally Administered B-glucans. Jana, 11, 2008 PDF DOCUMENT Novak M., Vetvicka V.: Beta-glucans, history, and the present: immunomodulatory aspects and mechanisms of action. Journal of Immunotoxicology, 5, 2008 PDF DOCUMENT Vetvicka V., Bohuslav Dvorak, Jana Vetvickova, Jan Richter, Jiri Krizan, Petr Sima and Jean-Claude Yvin: Orally-administered marine (1->3)- β-D-glucan Phycarine stimulates both humoral and cellular immunity. International Journal of Biological Macromolecules, 40, 2007 PDF DOCUMENT Vetvicka V., Vetvickova J.: An Evaluation of the Immunological Activities of Commercially Available B1, 3-Glucans. JANA, Vol. 10, No 1, 2007 PDF DOCUMENT Vetvicka V., Vetvickova J.: Immunostimulating Properties of Two Different B-glucans Isolated from Maitake Mushrooms (Grifola frondosa). JANA, Vol. 8, No 3, 33-39, 2005 web page Cathepsin D Benes P, Vetvicka V, Fusek M.: Cathepsin D-Many functions of one aspartic protease. Oncology Hematology 2008 PDF DOCUMENT Selicharova I, Sanda M, Mladkova J, Ohri SS, Vashishta A, Fusek M, Jiracek J, Vetvicka V.: 2-DE analysis of breast cancer cell lines 1833 and 4175 with distinct metastatic organ-specific potentials: Comparison with parental cell line MDA-MB-231.Oncology Reports 19, 2008 PDF DOCUMENT Ohri SS, Vashishta A, Proctor M, Fusek M, Vetvicka V.: The propeptide of cathepsin D increases proliferation, invasion and metastasis of breast cancer cells. Int J Oncology, 32, 2008 PDF DOCUMENT Ohri SS, Vashishta A, Proctor M, Fusek M, Vetvicka V.: Depletion of Procathepsin D Gene Expression by RNA Interference: A Potential Therapeutic Target for Breast Cancer. Cancer Biol. Therapy 6,* 2007* PDF DOCUMENT Vashishta A, Ohri SS, Proctor M, Fusek M, Vetvicka V.: Ribozyme-targeting procathepsin D and its effect on invasion and growth of breast cancer cells: an implication in breast cancer therapy. Int. J. Oncology 30, 2007 PDF DOCUMENT Saraswat-Ohri S., Vashishta A., Fusek M., Vetvicka V., Vetvickova J.: Procathepsin D expression correlates with invasive and metastatic phenotype of MDA-MB-231 derived cell lines. International Journal of Biological Macromolecules, 41, 204 - 209, 2007 PDF DOCUMENT Aruna Vashishta, Sujata Saraswat Ohria, Jana Vetvickova, Martin Fusek, Jitka Ulrichova, Vaclav Vetvicka: Procathepsin D secreted by HaCaT keratinocyte cells–A novel regulator of keratinocyte growth. European Journal of Cell Biology 86, 303-313, 2007 PDF DOCUMENT Fusek M., Vetvicka V., Vetvickova J.: Secretion of Cytokines in Breast Cancer Cells: The Molecular mechanism of Procathepsin D Proliferative Effects. Journal of Interferon & Cytokine Research 27: 191-199, 2007 PDF DOCUMENT Saraswat-Ohri S., Vashishta A., Fusek M., Vetvicka V., Vetvickova J.: Procathepsin D expression correlates with invasive and metastatic phenotype of MDA-MB-231 derived cell lines. International Journal of Biological Macromolecules, 41, 204 - 209, 2007 PDF DOCUMENT BOOKS Sima, P., Vetvicka, V.: Evolution of Immune Reactions, CRC Press, Boca Raton, 1990 Rihova, B., Vetvicka, V.: Immunological Disorders in Mice,CRC Press, Boca Raton, 1991 Fornusek, L., Vetvicka, V.:Immune System Accessory Cells,CRC Press, Boca Raton, 1992 Vetvicka, V., Sima, P., Cooper, E. L., Bilej, M., Roch, P.: Immunology of Annelids CRC Press, Boca Raton, 1994 Fernandez-Botran, R., Vetvicka, V.: Methods in Cellular Immunology, CRC Press, Boca Raton, 1995 Fusek, M. Vetvicka, V.: Aspartic Proteinases: Physiology and Pathology, CRC Press, Boca Raton, 1995 Vetvicka, V., Sima, P.: Evolutionary Mechanisms of Defense Reactions, Birkhäuser, 1998 Fernandez-Botran, R., Vetvicka, V.: Advanced Methods in Cellular Immunology, CRC Press, Boca Raton, 2000 Fernandez-Botran, R., Vetvicka, V.: Methods In Cellular Immunology, Second Edition, CRC Press, Boca Raton 2001